Tolerogenic transcriptome landscape in CD8+ T lymphocytes after exposure to erythrocyte-targeted antigens

Mice in research.

Tolerogenic transcriptome landscape in CD8+ T lymphocytes after exposure to erythrocyte-targeted antigens

First, you must be approved by regulatory authority, since you will be working with animals.

The kind they used was Male C57BL/6 mice. The age was 8-12 weeks.

These can be ordered through Envigo. If you are in America, the cost is not specified on the website for mysterious reasons. However, if you are in Italy, for example, it is perfectly clear that you will pay 24.30 euros per mice, with the price increasing as they get older.

CD45.1+ OTI mice were generated by crossing C57BL/6-Tg (TcraTcrb) 1100Mjb (OTI) mice (Jackson Laboratories) with C57BL/6-Ly5.1 (Charles River).

C57BL/6-Tg (TcraTcrb) 1100Mjb (OTI) don’t seem to be available at Jackson Laboratories. But the similar C57BL/6-Tg(TcraTcrb)1100Mjb/J and cost anywhere from $223.09 to $243.09 based on the age (3 weeks-9 weeks).

The Charles River strain asks me to sign up just to see the price, so I will not be pursuing that.

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